Vancomycin-Resistant Enterococcus in Kidney Transplant Patients
Author Information
Author(s): Freitas Maria Cecília S, Pacheco-Silva Alvaro, Barbosa Dulce, Silbert Suzane, Sader Hélio, Sesso Ricardo, Camargo Luis Fernando A
Primary Institution: Universidade Federal de São Paulo (UNIFESP)
Hypothesis
What is the prevalence of vancomycin-resistant Enterococcus (VRE) fecal colonization among kidney transplant patients?
Conclusion
Fecal VRE colonization rates in kidney transplant patients were as high as those reported for other high-risk groups.
Supporting Evidence
- The overall prevalence rate of fecal VRE colonization was 13.6%.
- Fecal colonization rates were 13.7% in group 1, 15.1% in group 2, and 12.4% in group 3.
- Fifty percent of all VRE isolates were either E. faecalis or E. faecium.
Takeaway
Doctors studied poop samples from kidney transplant patients to see how many had a germ called VRE. They found that a lot of these patients had it, just like other sick people in hospitals.
Methodology
Stool samples were collected from 280 kidney transplant patients and analyzed for VRE prevalence and associated risk factors.
Potential Biases
Potential bias due to incomplete data collection as not all patients returned for follow-up samples.
Limitations
Only 55% of patients had two stool cultures collected, which may have led to an underestimated colonization rate.
Participant Demographics
{"gender":{"male":163,"female":117},"race":{"white":187,"non-white":93},"primary_renal_disease":{"indeterminate":137,"hypertension":61,"glomerulonephritis":44,"diabetes_mellitus":11,"others":27}}
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website