Controlling Type 2 Diabetes with Diospyros peregrina Fruits
Author Information
Author(s): Dewanjee Saikat, Maiti Anup, Sahu Ranabir, Dua Tarun K., Mandal Vivekananda
Primary Institution: Jadavpur University
Hypothesis
The study investigates the effectiveness of hydroalcoholic extract of Diospyros peregrina in managing type 2 diabetes through antioxidant mechanisms.
Conclusion
The hydroalcoholic extract of Diospyros peregrina significantly reduces blood glucose and lipid levels in diabetic rats while enhancing antioxidant activity.
Supporting Evidence
- HDP significantly lowered fasting blood glucose levels in diabetic rats.
- HDP improved antioxidant enzyme activities in diabetic rats.
- Treatment with HDP reduced lipid peroxidation in diabetic rats.
- HDP increased liver glycogen levels in diabetic rats.
- HDP showed a dose-dependent effect on blood glucose and lipid levels.
Takeaway
Eating fruits from the Diospyros peregrina tree can help lower blood sugar and fat levels in diabetic rats, making it a potential natural treatment for diabetes.
Methodology
Diabetic rats were treated with hydroalcoholic extract of Diospyros peregrina at varying doses, and their blood glucose, lipid levels, and antioxidant markers were measured.
Limitations
The study was conducted on rats, and results may not directly translate to humans.
Participant Demographics
Wistar albino rats, specifically three-day-old pups.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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