The clinical efficacy of a novel smartphone-based salivary self-test for the prediction of pre-eclampsia, pregnancy-induced hypertension and intrauterine growth restriction: a prospective cohort study
2024

Smartphone Test for Predicting Pregnancy Complications

Sample size: 495 publication 10 minutes Evidence: moderate

Author Information

Author(s): Püschl Ida Catharina, Bonde Lisbeth, Gerds Thomas Alexander, Tackney Mia Sato, Quest James, Sorensen Bjarke Lund, Macklon Nicholas Stephen

Primary Institution: Zealand University Hospital, Roskilde, Denmark

Hypothesis

Can a smartphone-based salivary self-test predict pre-eclampsia, pregnancy-induced hypertension, and intrauterine growth restriction?

Conclusion

The study found that while the smartphone self-test was acceptable to pregnant women, it did not provide sufficient predictive value for clinical use.

Supporting Evidence

  • 34 women (6.9%) developed pre-eclampsia during the study.
  • The overall mean compliance rate for self-testing was 67%.
  • Significant discriminatory ability was achieved for only 8.2% of the analyses of individual color variables.

Takeaway

This study tested a new smartphone app that helps pregnant women check for serious health issues, but it wasn't good enough to be used in hospitals yet.

Methodology

Pregnant women performed weekly self-tests using a smartphone app to analyze salivary uric acid levels.

Limitations

The study's discriminatory ability was not consistent, and the sample size for certain outcomes was low.

Participant Demographics

Women aged 18 and older, with good communication skills in Danish or English, and having a smartphone.

Digital Object Identifier (DOI)

10.3389/fmed.2024.1385299

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