Alpha II Antiplasmin Deficiency Complicating Pregnancy: A Case Report
2011

Case Report of Alpha II Antiplasmin Deficiency in Pregnancy

Sample size: 1 publication Evidence: low

Author Information

Author(s): Brenda Dawley

Primary Institution: Joan C. Edwards School of Medicine

Hypothesis

How does alpha II antiplasmin deficiency affect pregnancy outcomes?

Conclusion

Alpha II antiplasmin deficiency resulted in multiple episodes of nonobstetrical hemorrhages requiring transfusion and ultimately preterm deliveries due to severe preeclampsia.

Supporting Evidence

  • Alpha II antiplasmin deficiency is inherited in an autosomal recessive fashion.
  • The patient experienced severe preeclampsia in both pregnancies.
  • Both infants had good outcomes despite the mother's complications.

Takeaway

A woman with a rare blood condition had two pregnancies that were complicated by severe bleeding and high blood pressure, but both she and her babies were okay in the end.

Methodology

Case report detailing the medical history and pregnancy complications of a patient with alpha II antiplasmin deficiency.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

30-year-old Caucasian female, Gravida 1, Para 0.

Digital Object Identifier (DOI)

10.1155/2011/698648

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