Rapid Spread of Chikungunya Virus Infection in Orissa, India
Author Information
Author(s): Dwibedi B., Sabat J., Mahapatra N., Kar S.K., Kerketta A.S., Hazra R.K., Parida S.K., Marai N.S., Beuria M.K.
Primary Institution: Regional Medical Research Centre (ICMR), Bhubaneswar, India
Hypothesis
The study investigates the emergence and spread of Chikungunya virus infection in Orissa, India.
Conclusion
The study confirmed the emergence of Chikungunya virus infection in Orissa and its rapid spread across a larger geographic area.
Supporting Evidence
- The first outbreak of Chikungunya in Orissa was confirmed in February 2006.
- The infection spread to 13 of 30 districts, affecting 79 villages by November 2007.
- The average seropositivity for CHIK specific IgM was 24 percent.
- Attack rates varied from 9 to 43 percent across different outbreaks.
- No deaths were recorded despite high morbidity.
- Aedes aegypti and Ae. albopictus were identified as the vectors for transmission.
- Symptoms included fever, joint pain, and fatigue, with most individuals recovering within a week.
- High workdays lost due to illness were reported, averaging 4 days.
Takeaway
Chikungunya is a virus that can make people very sick with fever and joint pain, and it spread quickly in Orissa, India.
Methodology
Epidemiological and laboratory investigations were conducted, including case history recording, clinical examinations, and blood sample collection for seroconfirmation.
Potential Biases
Potential bias due to reliance on self-reported symptoms and voluntary participation in blood sampling.
Limitations
The study did not include community seroprevalence data and relied on voluntary blood sample collection.
Participant Demographics
The study included individuals of all ages and both sexes, with a higher number of cases reported in the 16-45 year age group.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
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