Cost of severe hypoglycaemia in patients with type 1 diabetes in Spain and the cost-effectiveness of insulin lispro compared with regular human insulin in preventing severe hypoglycaemia
2008

Cost of Severe Hypoglycaemia in Type 1 Diabetes in Spain

Sample size: 100 publication Evidence: moderate

Author Information

Author(s): J. Reviriego, R. Gomis, J. P. Marañés, W. Ricart, P. Hudson, J. A. Sacristán

Primary Institution: Lilly S.A.

Hypothesis

To determine the costs of severe hypoglycaemia in patients with type 1 diabetes and the cost-effectiveness of insulin lispro compared to regular insulin.

Conclusion

The use of insulin lispro is associated with reductions in annual costs due to fewer severe hypoglycaemia episodes.

Supporting Evidence

  • The overall mean cost per episode of severe hypoglycaemia was €366.
  • Insulin lispro showed a lower incidence of severe hypoglycaemia compared to regular insulin.
  • Direct costs accounted for 65.4% of the total costs associated with severe hypoglycaemia.

Takeaway

This study shows that using a special type of insulin can help save money by preventing serious low blood sugar problems.

Methodology

A retrospective study reviewing clinical records of 100 type 1 diabetic patients from three Spanish health centres.

Limitations

The study only reviewed data from three centres, which may not represent the entire Spanish population.

Participant Demographics

51% male and 49% female, mean age 33.22 years, mean diabetes duration 16.9 years.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI of €124–380 for direct costs and €211–551 for total costs.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1111/j.1742-1241.2008.01783.x

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