Rapid assessment of fine needle aspiration and the final diagnosis – how often and why the diagnoses are changed
2006

Changes in Fine Needle Aspiration Diagnoses

Sample size: 1368 publication Evidence: moderate

Author Information

Author(s): Woon Carolyn, Bardales Ricardo H, Stanley Michael W, Stelow Edward B

Primary Institution: University of Minnesota

Hypothesis

How often do diagnoses from rapid interpretation of fine needle aspiration change by the final diagnosis?

Conclusion

Discrepancies between rapid interpretations and final diagnoses occur 5.8% of the time, often due to additional material available at the final diagnosis.

Supporting Evidence

  • 5.8% of rapid interpretations had discrepancies with final diagnoses.
  • Most discrepancies involved changes from non-diagnostic or benign to malignancy.
  • Different pathologists interpreted the rapid and final diagnoses in 31 cases.

Takeaway

Sometimes, doctors make mistakes when looking at samples quickly, and later they find out they were wrong about the diagnosis in a small number of cases.

Methodology

Cytology reports from 1/1/02 to 12/31/03 were reviewed for discrepancies between rapid interpretations and final diagnoses.

Potential Biases

Inter-observer variability may affect diagnosis accuracy due to different pathologists interpreting the samples.

Limitations

The study is limited to a single institution and may not represent broader practices.

Participant Demographics

Pathologists involved had subspecialty training in cytopathology.

Digital Object Identifier (DOI)

10.1186/1742-6413-3-25

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