Suspected Anaphylactic Reactions Associated with Anaesthesia
2009

Guidelines for Managing Anaphylactic Reactions During Anaesthesia

publication Evidence: moderate

Author Information

Author(s): Harper N J N, Dixon T, Dugué P, Edgar D M, Fay A, Gooi H C, Herriot R, Hopkins P, Hunter J M, Mirakian R, Pumphrey R S H, Seneviratne S L, Walls A F, Williams P, Wildsmith J A, Wood P, Nasser A S, Powell R K, Mirakhur R, Soar J

Primary Institution: Association of Anaesthetists of Great Britain and Ireland

Conclusion

Early recognition and optimal management of anaphylaxis during anaesthesia can prevent death or permanent disability.

Supporting Evidence

  • Anaphylaxis during anaesthesia is often misdiagnosed due to overlapping symptoms with other conditions.
  • Adrenaline is the most effective treatment for anaphylaxis and should be administered as soon as possible.
  • Collaboration between allergists and anaesthetists improves the investigation of suspected anaphylactic reactions.

Takeaway

If someone has a severe allergic reaction during surgery, doctors need to act quickly to help them. This guide helps doctors know what to do.

Methodology

This is a consensus document based on expert opinions and previous guidelines.

Limitations

The true incidence of anaphylaxis during anaesthesia is not well defined due to underreporting.

Participant Demographics

Anaphylaxis is more common in females and those with a history of atopy or asthma.

Digital Object Identifier (DOI)

10.1111/j.1365-2044.2008.05733.x

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