Genomics Update
2007

Linear Chromosomes in Bacteria: No Straight Edge Advantage?

publication

Author Information

Author(s): Michael Y Galperin

Primary Institution: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health

Conclusion

The study suggests that linear chromosomes in bacteria may not provide the expected advantages for maintaining long DNA molecules.

Supporting Evidence

  • The genome of Pichia stipitis allows for efficient fermentation of xylose into ethanol.
  • Pyrobaculum calidifontis is a model organism for studying hyperthermophilic enzymes.
  • Acinetobacter baumannii has evolved into a dangerous pathogen with high antibiotic resistance.

Takeaway

This study looks at whether having a straight chromosome helps bacteria, but it turns out that it might not be as helpful as we thought.

Digital Object Identifier (DOI)

10.1111/j.1462-2920.2007.01328.x

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication