Early Postnatal Protein-Calorie Malnutrition and Cognition: A Review of Human and Animal Studies
2011

Effects of Early Malnutrition on Cognitive Development

publication 10 minutes Evidence: moderate

Author Information

Author(s): Laus Maria Fernanda, Vales Lucas Duarte Manhas Ferreira, Costa Telma Maria Braga, Almeida Sebastião Sousa

Primary Institution: University of São Paulo

Hypothesis

How does early postnatal protein-calorie malnutrition affect cognitive development in humans and animals?

Conclusion

Early protein-calorie malnutrition significantly impairs cognitive development in both humans and animals.

Supporting Evidence

  • Malnutrition in early life leads to significant cognitive impairments.
  • Animal studies show that malnourished rats exhibit learning and memory deficits.
  • Human studies indicate that malnutrition negatively affects children's IQ and school performance.
  • Supplementation can improve cognitive outcomes in malnourished children.
  • Environmental factors also play a crucial role in cognitive development.

Takeaway

Not eating enough protein and calories when you're a baby can make it harder to think and learn as you grow up.

Methodology

The review analyzed human and animal studies on malnutrition and cognitive development using various search techniques and criteria.

Potential Biases

Potential biases in the selection of studies and the interpretation of correlational data.

Limitations

The review is limited by the small number of studies directly linking malnutrition to cognitive outcomes.

Participant Demographics

Studies primarily involved children from developing countries and rodents.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/ijerph8020590

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