Impact of premenstrual syndrome and premenstrual dysphoric disorder on maternal antenatal depression
2024

Impact of PMS and PMDD on Maternal Depression During Pregnancy

Sample size: 212 publication Evidence: moderate

Author Information

Author(s): Ihara Nozomi, Sato Yoko, Ikeda Subaru, Matsufuji Hiromi, Kikuchi Kimiyo, Suetsugu Yoshiko, Hikita Naoko, Morokuma Seiichi

Primary Institution: Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

Hypothesis

This study aimed to determine the association of premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD) with maternal antenatal depression.

Conclusion

The study found that having a history of PMS or PMDD is significantly associated with maternal antenatal depression.

Supporting Evidence

  • Having PMDD was associated with an odds ratio of 3.54 for antenatal depression.
  • Having PMS was associated with an odds ratio of 2.31 for antenatal depression.
  • The study included 212 pregnant women between 24 and 28 weeks of gestation.
  • Screening for PMS and PMDD may help in preventing perinatal depression.

Takeaway

If a mom had PMS or PMDD before, she might feel sad during pregnancy, so it's important to check on her feelings early.

Methodology

This was a cross-sectional, online questionnaire-based observational study.

Potential Biases

Self-reported data may introduce recall bias and issues with data reliability.

Limitations

The study used a screening test for perinatal depression rather than a final diagnosis, and there may have been selection bias due to the web-based survey.

Participant Demographics

Participants were pregnant women aged ≥20 years with singleton pregnancies between 24 and 28 weeks of gestation.

Statistical Information

P-Value

0.02 for PMDD, 0.03 for PMS

Confidence Interval

[1.26–9.93] for PMDD, [1.10–4.87] for PMS

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0315628

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