A review of bronchiolitis obliterans syndrome and therapeutic strategies
2011

Bronchiolitis Obliterans Syndrome and Treatment Strategies

publication Evidence: moderate

Author Information

Author(s): Hayes Don Jr

Primary Institution: The Ohio State University

Hypothesis

What are the therapeutic strategies for managing bronchiolitis obliterans syndrome (BOS) in lung transplant recipients?

Conclusion

Lung retransplantation remains a controversial but improving option for patients with bronchiolitis obliterans syndrome.

Supporting Evidence

  • BOS is the leading cause of death beyond the first year post lung transplantation.
  • Survival rates for lung retransplantation have improved over the past decade.
  • Routine screening for BOS is crucial for early intervention.

Takeaway

Bronchiolitis obliterans syndrome is a serious condition that can occur after lung transplants, and while treatments exist, they mainly help slow down the problem rather than fix it.

Methodology

This manuscript reviews bronchiolitis obliterans syndrome and current therapeutic strategies, including outcomes for lung retransplantation.

Limitations

The therapies available for BOS are limited and primarily serve to slow the decline in pulmonary function.

Digital Object Identifier (DOI)

10.1186/1749-8090-6-92

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