Diet Supplementation with Ketoanalogues, Inulin, and Calcium Citrate in Chronic Kidney Disease
Author Information
Author(s): Calderón-Juárez Martín, Saavedra-Fuentes Nadia, Del Castillo-Loreto Karla Guadalupe, Castillo-Salinas Juan Carlos, Lerma Claudia
Primary Institution: Universidad Nacional Autónoma de México
Hypothesis
Does the addition of ketoanalogues, inulin, and calcium citrate to a low-protein diet improve kidney function and symptoms in patients with chronic kidney disease?
Conclusion
The study suggests that adding ketoanalogues, inulin, and calcium citrate to a low-protein diet may improve kidney function and reduce symptoms in patients with chronic kidney disease.
Supporting Evidence
- The study included 76 patients with chronic kidney disease stages 3 and 4.
- Participants showed a slight increase in eGFR and a decrease in CKD-related symptoms after 6 months.
- Statistical analysis indicated significant changes in eGFR and symptom severity.
- Patients were followed through two clinic visits at 3 and 6 months after diet supplementation.
Takeaway
This study looked at how a special diet with certain supplements can help people with kidney problems feel better and improve their kidney function.
Methodology
This was a retrospective cohort study that followed 76 adult patients with chronic kidney disease over six months after they were prescribed a low-protein diet supplemented with ketoanalogues, inulin, and calcium citrate.
Potential Biases
Potential bias due to the observational nature of the study and loss of participants during follow-up.
Limitations
The study's retrospective design limits the ability to establish causation, and there was data loss during follow-up.
Participant Demographics
76 adult patients with chronic kidney disease stages 3 and 4, not treated with renal replacement therapy.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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