Estrogen Monitoring in Frozen Embryo Transfer Cycles
Author Information
Author(s): Niu Zhihong, Feng Yun, Sun Yijuan, Zhang Aijun, Zhang Huiqin
Primary Institution: IVF-unit, Department of Obstetrics and Gynecology, RuiJin Hospital Affiliated to Shanghai Jiaotong University, PR China
Hypothesis
Is estrogen level monitoring necessary in artificial frozen-thawed embryo transfer cycles using a step-up regime without pituitary suppression?
Conclusion
The serum estradiol level did not predict pregnancy success in hormone replacement FET cycles, suggesting that oestradiol monitoring in this method of endometrial preparation is unnecessary.
Supporting Evidence
- Patients with different levels of serum oestradiol showed similar pregnancy rates.
- Endometrial thickness did not vary significantly with different estradiol levels.
- The study suggests that monitoring estradiol levels may not provide useful information for predicting pregnancy success.
Takeaway
This study found that checking estrogen levels during certain fertility treatments doesn't help predict if a pregnancy will happen, so it might not be needed.
Methodology
This retrospective cohort study included data from 212 women undergoing 274 frozen-thawed embryo transfer cycles, comparing pregnancy outcomes based on serum estradiol levels.
Potential Biases
Potential selection bias due to the retrospective nature of the study.
Limitations
The study is retrospective and may not account for all variables affecting pregnancy outcomes.
Participant Demographics
The study included 212 women with functioning ovaries undergoing frozen-thawed embryo transfer.
Statistical Information
Statistical Significance
P > 0.05
Digital Object Identifier (DOI)
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