Age- and sex-standardised prevalence rates of fatigue in a large hospital-based sample of cancer patients
2011

Prevalence of Fatigue in Cancer Patients

Sample size: 1494 publication 10 minutes Evidence: moderate

Author Information

Author(s): Singer S, Kuhnt S, Zwerenz R, Eckert K, Hofmeister D, Dietz A, Giesinger J, Hauss J, Papsdorf K, Briest S, Brown A

Primary Institution: University of Leipzig

Hypothesis

What are the age- and sex-standardised prevalence rates of cancer-related fatigue in different groups of patients?

Conclusion

About a third of cancer patients are classified as fatigued at the beginning of treatment, with prevalence rates varying significantly between different patient groups.

Supporting Evidence

  • 32% of patients were fatigued at hospital admission.
  • 40% reported fatigue at discharge.
  • 34% were fatigued six months after treatment.

Takeaway

Many cancer patients feel very tired, especially when they start treatment, and this tiredness can change over time.

Methodology

A prospective cohort study measuring fatigue at three time points using the Multidimensional Fatigue Inventory.

Potential Biases

Patients who declined to participate may have been more fatigued, potentially skewing results.

Limitations

The study could not collect biological data or assess all referred patients, which may lead to underestimating fatigue prevalence.

Participant Demographics

The sample included 891 males (59.6%) and 603 females (40.4%), with a mean age of 60.2 years.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1038/bjc.2011.251

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