Crystal structure and Hirshfeld surface analysis of the chalcone derivative (2E)-3-[4-(di­phenyl­amino)phen­yl]-1-[4-(prop-1-yn-2-yl­oxy)phen­yl]prop-2-en-1-one
2025

Crystal Structure of a Chalcone Derivative

publication Evidence: moderate

Author Information

Author(s): Madhan Sundarasamy, NizamMohideen M., Viswanathan Vijayan, Velmurugan Devadasan

Primary Institution: University of Madras

Hypothesis

The study aims to analyze the crystal structure and Hirshfeld surface of a specific chalcone derivative.

Conclusion

The chalcone derivative exhibits an s-cis conformation and is stabilized by hydrogen bonds and weak interactions in the crystal structure.

Supporting Evidence

  • The molecule adopts an s-cis conformation with respect to the C=O and C=C bonds.
  • The tri­phenyl­amine moiety has a propeller-type shape.
  • Molecules are linked by C—H⋯O hydrogen bonds, forming chains in the crystal.

Takeaway

Scientists studied a special molecule called a chalcone and found out how it is arranged in a crystal, which helps us understand its properties better.

Methodology

The study involved synthesizing the chalcone derivative and analyzing its crystal structure using X-ray diffraction and Hirshfeld surface analysis.

Digital Object Identifier (DOI)

10.1107/S2056989024011721

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