Coffee and Genetics Affect Breast Volume in Young Women
Author Information
Author(s): H Jernström, M Henningson, U Johansson, H Olsson
Primary Institution: Lund University
Hypothesis
Does coffee intake and CYP1A2*1F genotype influence breast volume in young women?
Conclusion
The study found that coffee consumption is associated with lower breast volume in women with the CYP1A2*1F C-allele.
Supporting Evidence
- Coffee consumption was positively associated with lower breast volume in women with the C-allele.
- No significant association was found between coffee consumption and breast volume in women with the A/A genotype.
- The interaction between coffee intake and CYP1A2*1F genotype remained significant after adjusting for BRCA1/2 mutation status.
Takeaway
Drinking coffee might make some women's breasts smaller, especially if they have a certain gene.
Methodology
The study involved 269 young healthy women from high-risk breast cancer families, measuring breast volume and analyzing CYP1A2*1F genotype and coffee intake.
Potential Biases
Potential bias due to self-reported coffee consumption and the exclusion of certain demographics.
Limitations
The study did not include women who were currently breastfeeding or had previous breast surgeries.
Participant Demographics
Young healthy Swedish women from breast cancer high-risk families, median age 29.
Statistical Information
P-Value
0.02
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website