Maculopathies: A Systematic Literature Review on Pathophysiology, Public Health, and Treatment
2024

Maculopathies: A Systematic Literature Review on Pathophysiology, Public Health, and Treatment

publication Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Pantelidou Maria E, Sunnucks David, Pantelidis Elias P

Conclusion

Maculopathies are diverse diseases that cause severe central vision loss, and while current treatments are limited, ongoing research into gene therapy and stem cell treatments offers hope for future improvements.

Supporting Evidence

  • Age-related macular degeneration (AMD) is the leading cause of visual loss in older populations.
  • Diabetic maculopathy is the most prevalent cause of visual impairment in those with diabetic retinopathy.
  • Stem cell research shows promise for future therapies that could slow or prevent progressive visual loss.

Takeaway

Maculopathies are eye diseases that can make it hard to see clearly, especially in the center of your vision. Scientists are working on new treatments to help people with these conditions.

Methodology

This systematic review followed PRISMA guidelines and included literature searches from multiple databases.

Potential Biases

The quality assessment was performed by independent reviewers to reduce publication bias.

Limitations

The review may be limited by the availability of peer-reviewed articles and the focus on English language documents.

Digital Object Identifier (DOI)

10.7759/cureus.74911

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication