Risk Factors for Nine-Year Mortality of Older Patients with Cognitive Impairment at Admission
2024
Risk Factors for Nine-Year Mortality in Older Patients with Cognitive Impairment
Sample size: 612
publication
Evidence: high
Author Information
Author(s): Yamamoto Hiroshi, Ogawa Kenichi, Hisamatstu Yasushi, Ishitake Tatsuya
Primary Institution: Yamamoto Memorial Hospital
Hypothesis
Cognitive impairment at admission negatively impacts mortality and hospital outcomes in older patients.
Conclusion
Malnutrition, pneumonia, and cancer significantly decrease survival rates in patients with cognitive impairment.
Supporting Evidence
- 349 patients (57.0%) died during follow-up.
- Cognitive function was classified into three categories: Incomplete, Abnormal, and Normal.
- Mortality hazard increased with 'Incomplete' cognitive function (HR 3.526).
- Mortality hazard increased with 'Abnormal' cognitive function (HR 1.676).
Takeaway
Older patients with memory problems are more likely to die, especially if they also have issues like malnutrition or cancer.
Methodology
The study used Kaplan-Meier and Cox regression models to analyze mortality and survival rates among 612 acute inpatients aged 65 and older.
Participant Demographics
Mean age 82.1 years, 55.9% female.
Statistical Information
P-Value
p<0.0001
Confidence Interval
CI 95% 2.388-5.206
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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