Using the net benefit regression framework to construct cost-effectiveness acceptability curves: an example using data from a trial of external loop recorders versus Holter monitoring for ambulatory monitoring of 'community acquired' syncope
2006

Cost-Effectiveness of Loop Recorders vs Holter Monitors for Syncope

Sample size: 100 publication Evidence: moderate

Author Information

Author(s): Jeffrey S Hoch, Marie Antoinette Rockx, Andrew D Krahn

Primary Institution: Centre for Research on Inner City Health, St. Michael's Hospital, Toronto, Canada

Hypothesis

Can the net benefit regression framework be used to construct cost-effectiveness acceptability curves for ambulatory monitoring of syncope?

Conclusion

The net benefit regression framework is effective for constructing cost-effectiveness acceptability curves, indicating that loop recorders may be cost-effective compared to Holter monitors.

Supporting Evidence

  • Loop recorders had a higher success rate in diagnosing symptoms compared to Holter monitors.
  • The incremental cost-effectiveness ratio for loop recorders was $1,096 per additional successful diagnosis.
  • The study used a sample size of 100 patients to compare the two monitoring methods.

Takeaway

This study looked at two types of heart monitors to see which one is better for patients who faint. It found that one type, the loop recorder, works better even though it costs more.

Methodology

Patients were randomized to receive either a loop recorder or a Holter monitor, and costs and outcomes were analyzed to determine cost-effectiveness.

Limitations

The study's findings may not be generalizable due to the specific patient population and the cost data being based on a single health insurance plan.

Participant Demographics

Patients referred for ambulatory monitoring with syncope or presyncope.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1472-6963-6-68

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication