Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region
2007

Celiac Disease and Dental Enamel Hypoplasia

Sample size: 100 publication 10 minutes Evidence: moderate

Author Information

Author(s): Maurizio Procaccini, Giuseppina Campisi, Pantaleo Bufo, Domenico Compilato, Claudia Massaccesi, Carlo Catassi, Lorenzo Lo Muzio

Primary Institution: Istituto di Scienze Odontostomatologiche, Università Politecnica delle Marche, Italy

Hypothesis

Is there a prevalence of dental enamel hypoplasia in patients with celiac disease compared to healthy controls?

Conclusion

The prevalence of enamel hypoplasia was not higher in the study population than in the control group, but recurrent aphthous stomatitis was significantly more frequent in patients with celiac disease.

Supporting Evidence

  • Enamel hypoplasia was observed in 26% of celiac patients compared to 16% in controls.
  • Recurrent aphthous stomatitis occurred in 36% of celiac patients versus 12% in controls.
  • The study found no significant difference in enamel defects between celiac patients and healthy controls.

Takeaway

Kids with celiac disease don't have more problems with their teeth than kids without it, but they do get mouth sores more often.

Methodology

Fifty patients with celiac disease and fifty healthy controls were evaluated for dental and oral conditions by a trained examiner.

Potential Biases

Potential bias due to reliance on self-reported data from parents regarding oral lesions.

Limitations

The study relied on medical history and clinical features for diagnosis, which may not capture all cases.

Participant Demographics

Participants were aged 3 to 25 years, matched for age, gender, and geographical area.

Statistical Information

P-Value

0.0091

Confidence Interval

95% CI = 1.4725: 11.552

Statistical Significance

p = 0.0091

Digital Object Identifier (DOI)

10.1186/1746-160X-3-25

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