Lymphomas with Primary Gastrointestinal Presentation: A Study from Southern India
Author Information
Author(s): Muacevic Alexander, Adler John R, George Dona Maria, Lakshmanan Archana
Primary Institution: Apollo Hospitals, Chennai, IND
Hypothesis
This study aimed to analyze the demography, anatomic distribution, histological subtypes, and immunomorphological characteristics of all lymphomas with a primary GI presentation.
Conclusion
The study found that GI lymphomas are heterogeneous, with distinct prognoses and treatment strategies, and accurate diagnosis is crucial for effective management.
Supporting Evidence
- Out of 2,455 lymphoma cases diagnosed, 156 presented with primary GI symptoms.
- The stomach was the most common site for GI lymphomas, followed by the small intestine and large intestine.
- Most lymphomas involving the GI tract were non-Hodgkin lymphoma (97%).
- Diffuse large B-cell lymphoma was the most frequent subtype, accounting for 65.3% of cases.
Takeaway
This study looked at lymphomas that start in the stomach and intestines, finding that most cases are in older men and that the stomach is the most common place for these cancers.
Methodology
A retrospective study covering the period from 2018 to 2022 involving all cases of lymphomas with primary GI presentation, categorized based on morphological and immunophenotypic criteria.
Limitations
The study lacked follow-up data and detailed clinical histories related to coeliac disease and transplantation history.
Participant Demographics
The majority of patients were older, with a peak incidence in the sixth decade of life; 72.5% were male and 27.5% were female.
Digital Object Identifier (DOI)
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