The Modulatory Effects of Transcranial Alternating Current Stimulation on Brain Oscillatory Patterns in the Beta Band in Healthy Older Adults
2024

Effects of Transcranial Alternating Current Stimulation on Brain Waves in Older Adults

Sample size: 15 publication 10 minutes Evidence: moderate

Author Information

Author(s): Morales Fajardo Kenya, Yan Xuanteng, Lungoci George, Casado Sánchez Monserrat, Mitsis Georgios D., Boudrias Marie-Hélène

Primary Institution: McGill University

Hypothesis

70 Hz HD-tACS would decrease resting-state beta power and promote a more positive MRBD, while 20 Hz HD-tACS would increase beta power at rest and induce more negative MRBD.

Conclusion

The study found that HD-tACS can modulate beta brain oscillations with frequency specificity, particularly showing significant effects with 20 Hz stimulation.

Supporting Evidence

  • 20 Hz HD-tACS significantly reduced beta power at electrodes C3 and CP3.
  • 70 Hz HD-tACS did not show significant effects on beta power.
  • MRBD values became more negative after 20 Hz HD-tACS and more positive after 70 Hz HD-tACS.

Takeaway

This study looked at how a special brain stimulation technique can change brain waves in older people, helping us understand how to improve their movement and thinking.

Methodology

The study involved 15 healthy older adults who underwent 10 minutes of either 20 Hz or 70 Hz HD-tACS or Sham stimulation while their EEG was recorded during a handgrip task.

Potential Biases

Potential biases include participant selection and the subjective nature of self-reported outcomes.

Limitations

The study's findings may not be generalizable due to the small sample size and the specific age range of participants.

Participant Demographics

15 healthy older adults (7 males and 8 females) over 65 years old.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/brainsci14121284

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