Long-Term Management of Esophageal Varices by Endoscopic Sclerotherapy
Author Information
Author(s): DINESH K. BHARGAVA, S. DASARATHY, SUSHMA SAKSENA
Primary Institution: All India Institute of Medical Sciences, New Delhi, India
Hypothesis
Endoscopic sclerotherapy is an effective long-term management strategy for esophageal variceal bleeding.
Conclusion
Endoscopic sclerotherapy significantly reduces rebleeding and improves survival rates in patients with esophageal varices.
Supporting Evidence
- Variceal eradication was achieved in 80% of patients with cirrhosis, 87% with NCPF, and 90% with EHO.
- The probability of survival at 10 years was higher in patients with EHO (88%) and NCPF (80%) than in patients with cirrhosis (50%).
- Rebleeding occurred in 27.7% of patients with cirrhosis, 24.3% with NCPF, and 11% with EHO.
- Patients with Child's A status had a longer bleeding-free period compared to those with Child's B and C status.
Takeaway
Doctors can help people with bleeding veins in their esophagus by using a special treatment that makes the veins go away, which helps them feel better and live longer.
Methodology
The study reviewed the outcomes of 566 patients treated with endoscopic sclerotherapy for esophageal varices over a 12-year period.
Limitations
Some patients were lost to follow-up, and the study was retrospective.
Participant Demographics
{"total_patients":566,"cirrhosis":342,"NCPF":107,"EHO":117,"gender_ratio":{"male":302,"female":40},"age_mean":{"cirrhosis":43.6,"NCPF":29.8,"EHO":15.1}}
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
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