Trichostatin A Selectively Suppresses the Cold-Induced Transcription of the ZmDREB1 Gene in Maize
2011

How Cold Affects Gene Expression in Maize

Sample size: 30 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hu Yong Zhang, Lu Zhao, Lin Li, Jun He, Shibin Zhou, Kun Yang, Fei Huang, Min Jiang, Li Li, Lijia

Primary Institution: State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China

Hypothesis

Cold treatment induces the expression of histone deacetylases (HDACs) that regulate the transcription of cold-responsive genes in maize.

Conclusion

The study found that HDACs positively regulate the expression of the cold-induced ZmDREB1 gene through histone modification and chromatin changes.

Supporting Evidence

  • Cold treatment increases the expression of HDACs in maize seedlings.
  • TSA treatment inhibits the expression of cold-responsive genes ZmDREB1 and ZmCOR413.
  • Histone acetylation levels decrease in response to cold stress.
  • TSA treatment leads to hyperacetylation in the ZmDREB1 promoter region.
  • HDACs are implicated in the cold signaling pathway in maize.

Takeaway

When maize plants get cold, they change how their genes work to survive, and a special chemical can help us see how this happens.

Methodology

The study used cold treatment and the HDAC inhibitor trichostatin A (TSA) to analyze gene expression changes in maize seedlings.

Limitations

The study primarily focuses on specific genes and may not encompass all cold-responsive mechanisms in maize.

Participant Demographics

Maize seedlings (Zea mays L. inbred line Huangzao 4) were used in the experiments.

Digital Object Identifier (DOI)

10.1371/journal.pone.0022132

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