ASSOCIATION BETWEEN DIET AND RETINAL IMAGING MARKER IN THE PREVENT DEMENTIA STUDY
2024
Diet and Eye Health in Dementia Study
Sample size: 86
publication
Evidence: low
Author Information
Author(s): Gregory Sarah, Gibbon Samuel, MacGillivray Thomas, Terrera Graciela Muniz
Primary Institution: University of Edinburgh
Hypothesis
Is there an association between diet and retinal imaging markers in individuals at risk for dementia?
Conclusion
Higher dietary manganese intake is associated with lower CRAE HZC density in the right eye.
Supporting Evidence
- Participants had a moderate mean Pyramid score of 8.16.
- The dietary intake of manganese was 4.77 mg.
- There was no evidence of associations between the Pyramid score and dietary manganese in the left eye.
- Longitudinal associations were not observed in the follow-up data.
Takeaway
Eating certain foods might help keep our eyes and brains healthy, especially for people at risk of dementia.
Methodology
The study used generalised additive models to analyze associations between diet and retinal imaging markers.
Limitations
The sample size is small and further research is needed with a larger group.
Participant Demographics
Mean age 50.87 years, majority female (57%), with 36% being APOEe4 carriers.
Digital Object Identifier (DOI)
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