Nano-chitosan-coated, green-synthesized selenium nanoparticles as a novel antifungal agent against Sclerotinia sclerotiorum: in vitro study
2025

New Antifungal Agent from Selenium Nanoparticles

Sample size: 15 publication 10 minutes Evidence: high

Author Information

Author(s): Desouky Mohamed M., Abou-Saleh Radwa H., Moussa Tarek A., Fahmy Heba M.

Primary Institution: Cairo University

Hypothesis

Can nano-chitosan-coated selenium nanoparticles effectively inhibit the growth of Sclerotinia sclerotiorum?

Conclusion

The study found that the nano-chitosan-coated selenium nanoparticles exhibited 100% antifungal activity against Sclerotinia sclerotiorum at a minimum inhibitory concentration of 0.5 ppm.

Supporting Evidence

  • The nanocomposite showed a significant increase in antifungal efficacy compared to bulk structures.
  • At a minimum inhibitory concentration of 0.5 ppm, the nanocomposite exhibited 100% inhibitory activity.
  • Fungal hyphae treated with the nanocomposite showed substantial damage and deformation.

Takeaway

Researchers created tiny particles from selenium and chitosan that can stop a harmful fungus from growing, which could help protect plants.

Methodology

The study involved synthesizing selenium nanoparticles using citrus peel extracts and coating them with chitosan, followed by testing their antifungal activity in vitro.

Limitations

The study primarily focused on in vitro conditions, which may not fully represent field conditions.

Statistical Information

P-Value

0.5

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/s41598-024-79574-x

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