The European Chemical Biology Database (ECBD) serves as the central repository for data generated by the EU-OPENSCREEN research infrastructure consortium.
2024

European Chemical Biology Database: A Central Hub for Chemical Biology Data

publication Evidence: high

Author Information

Author(s): Škuta Ctibor, Müller Tomáš, Voršilák Milan, Popr Martin, Epp Trevor, Skopelitou Katholiki, Rossella Federica, Herzog Katja, Stechmann Bahne, Gribbon Philip, Bartůněk Petr

Primary Institution: CZ-OPENSCREEN: National Infrastructure for Chemical Biology, Institute of Molecular Genetics of the Czech Academy of Sciences

Conclusion

The European Chemical Biology Database (ECBD) provides a centralized, open-access repository for chemical biology data, ensuring high-quality datasets that support drug discovery.

Supporting Evidence

  • The ECBD is developed according to FAIR principles, emphasizing data findability, accessibility, interoperability, and reusability.
  • ECBD stores both positive and negative results from the entire chemical biology project pipeline.
  • Currently, 89 datasets have been submitted to ECBD, with 48 already publicly accessible.

Takeaway

The ECBD is like a big library where scientists can find and share information about different chemicals and their effects, helping them discover new medicines.

Methodology

Data is collected from various assays using a large library of compounds, following standardized procedures to ensure quality and consistency.

Limitations

Data availability is subject to embargo periods, and not all datasets are currently public.

Digital Object Identifier (DOI)

10.1093/nar/gkae904

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