Study on Multiple Intracranial Aneurysms in Tibetan Patients
Author Information
Author(s): Wang Dongliang, Wuli Jiuqi, Cao Xudong, Wang Bin, Ren Zeng, Weng Yu, Kexue Wu
Primary Institution: Tibet Autonomous Region People’s Hospital
Hypothesis
Patients with multiple intracranial aneurysms (MIAs) may have poorer outcomes after rupture than patients with single intracranial aneurysms (SIAs).
Conclusion
Patients with MIAs on the Tibetan Plateau are more likely to be female, smokers, alcohol drinkers, and hypertensive, and endovascular treatment is superior to conservative management but not significantly better than craniotomy.
Supporting Evidence
- Patients with MIAs were more likely to be female, smokers, alcohol drinkers, and hypertensive.
- The size of ruptured aneurysms was significantly larger in MIAs compared to SIAs.
- Endovascular treatment showed better outcomes than conservative management.
Takeaway
This study looked at patients with brain aneurysms in Tibet and found that those with multiple aneurysms tend to have different characteristics and outcomes compared to those with just one.
Methodology
The study retrospectively analyzed clinical data of 68 patients with MIAs and 68 patients with SIAs using univariate and multivariate analyses.
Potential Biases
The choice of treatment was based on patient preference rather than a randomized controlled trial.
Limitations
The study was confined to one center, and the incidence and rupture rates of MIAs could not be accurately ascertained due to potential biases.
Participant Demographics
The mean age of participants was 51.0 years, with a higher prevalence of females in the MIA group (75%).
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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