Controversies in the management of advanced prostate cancer
1999
Management of Advanced Prostate Cancer
publication
Author Information
Author(s): Tyrrell C J
Primary Institution: Oncology Research Unit, Derriford Hospital, Plymouth, UK
Hypothesis
Does combined androgen blockade (CAB) provide an advantage over surgical castration in treating advanced prostate cancer?
Conclusion
Combined androgen blockade may offer benefits over surgical castration, with fewer side effects from certain anti-androgens.
Supporting Evidence
- Combined androgen blockade (CAB) has been compared with castration alone in numerous clinical trials.
- Some trials show an advantage of CAB over castration, while others report no significant difference.
- Bicalutamide may have a lower incidence of side effects compared to other anti-androgens.
Takeaway
This study looks at different treatments for advanced prostate cancer and suggests that a combination of therapies might work better than just one.
Digital Object Identifier (DOI)
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