Oxalis erythrorhiza Gillies ex Hooker et Arnott (Oxalidaceae): Chemical Analysis, Biological In Vitro and In Vivo Properties and Behavioral Effects
2024

Study of Oxalis erythrorhiza: Health Benefits and Chemical Properties

Sample size: 60 publication 10 minutes Evidence: moderate

Author Information

Author(s): Gómez Jessica, Simirgiotis Mario J., Kruse María Sol, Gamarra-Luques Carlos, Lima Beatriz, Zaragoza José, Piñeiro Mauricio, Tapia Alejandro, Coirini Héctor, Rey Mariana

Primary Institution: Instituto de Biotecnología-Instituto de Ciencias Básicas, Universidad Nacional de San Juan, Argentina

Hypothesis

The decoction and methanolic extract of Oxalis erythrorhiza possess antioxidant, anti-inflammatory, and cytotoxic properties.

Conclusion

Oxalis erythrorhiza shows potential health benefits, including antioxidant and anti-inflammatory effects, but further research is needed to understand its mechanisms.

Supporting Evidence

  • The decoction and methanolic extract showed strong antioxidant activities.
  • DOe demonstrated significant inhibitory effects on COX-2.
  • DOe produced selective cytotoxic effects on cancer cells.
  • HDOeS exhibited lower anxiety-like behavior in rats.
  • DOeS showed reduced serum cholesterol levels compared to control.

Takeaway

This study found that a plant called Oxalis erythrorhiza can help with health issues like inflammation and anxiety, but we need to learn more about how it works.

Methodology

The study involved chemical analysis using UHPLC-ESI-QTOF-MS and various in vitro and in vivo assays to evaluate antioxidant, anti-inflammatory, and cytotoxic properties.

Limitations

The study's findings require further investigation to fully elucidate the mechanisms of action of the extracts.

Participant Demographics

Adult male Sprague-Dawley rats were used in the in vivo studies.

Statistical Information

P-Value

0.002

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/antiox13121494

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