Right Ventricular Dysfunction Before Left Ventricular Dysfunction in Paced Patients
Author Information
Author(s): Dwivedi SK, Bansal Sandeep, Puri Aniket, Makharia MK, Narain VS, Saran RK, Hasan M, Puri VK
Primary Institution: King George's Medical University, Lucknow, India
Hypothesis
The study aims to evaluate the sequence of diastolic and systolic dysfunction in patients with right ventricular apical pacing.
Conclusion
Right ventricular dysfunction is the first abnormality that occurs in patients with VVI pacing, followed by left ventricular dysfunction.
Supporting Evidence
- Diastolic dysfunction in the right ventricle was the first change observed after VVI pacing.
- Left ventricular dysfunction appeared later, at 1 month after pacing.
- The study followed patients for 6 months to observe changes in cardiac function.
Takeaway
When patients get a pacemaker in their heart, the right side starts to have problems before the left side does.
Methodology
Patients with symptomatic bradycardia underwent VVI pacemaker implantation and were followed up with echocardiographic examinations at baseline, 1 week, 1 month, and 6 months.
Potential Biases
Potential bias due to the exclusion of patients with other pacing modes and reliance on echocardiographic measurements.
Limitations
Echocardiographic evaluation of RV size may not be reliable due to variability, and the study included patients with varying baseline ejection fractions.
Participant Demographics
Mean age 65.6 years, 66.7% males, with 75.6% having complete heart block.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
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