2,4-Bis(4-fluorophenyl)-2,3-dihydro-1H-1,5-benzodiazepine
2011
Crystal Structure of a New Benzodiazepine Compound
publication
Evidence: moderate
Author Information
Author(s): Baktır Zeliha, Akkurt Mehmet, Samshuddin S., Narayana B., Yathirajan H. S.
Primary Institution: Erciyes University
Conclusion
The study successfully reports the crystal structure of a new benzodiazepine compound, revealing its unique conformation and interactions.
Supporting Evidence
- The compound's seven-membered ring adopts a distorted-boat conformation.
- Two weak hydrogen bonds link inversion-related molecules.
- Dihedral angles between the benzene rings and fluorophenyl substituents were measured.
Takeaway
Scientists made a new type of medicine and looked at its tiny structure to see how it is shaped and how it sticks together.
Methodology
The compound was synthesized and its crystal structure was analyzed using X-ray diffraction.
Digital Object Identifier (DOI)
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