Pyrimidin-2-amine–1-phenyl­cyclo­pentane-1-carb­oxy­lic acid (1/1)
2011

Crystal Structure of Pyrimidin-2-amine and 1-phenylcyclopentane-1-carboxylic Acid Co-crystal

publication Evidence: moderate

Author Information

Author(s): He Guangwen, Aitipamula Srinivasulu, Chow Pui Shan, Tan Reginald B. H.

Primary Institution: Institute of Chemical and Engineering Sciences, A*STAR

Hypothesis

The study investigates the crystal structure of a co-crystal formed by pyrimidin-2-amine and 1-phenylcyclopentane-1-carboxylic acid.

Conclusion

The co-crystal exhibits strong hydrogen bonding interactions that direct its supramolecular structure.

Supporting Evidence

  • The co-crystal contains one molecule of pyrimidin-2-amine and one molecule of 1-phenylcyclopentane-1-carboxylic acid.
  • Strong hydrogen bonds were observed between the components, directing the structure.
  • Four-component supramolecular units self-assemble in the crystal structure.

Takeaway

The researchers looked at how two chemicals stick together to form a new structure, which is held together by strong connections called hydrogen bonds.

Methodology

The co-crystal was formed by dissolving pyrimidin-2-amine and 1-phenylcyclopentane-1-carboxylic acid in ethyl acetate and allowing the solution to evaporate.

Digital Object Identifier (DOI)

10.1107/S1600536811003667

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