Prediction of peak pressure from clinical and radiological measurements in patients with diabetes
2008

Predicting Peak Pressure in Diabetic Patients

Sample size: 93 publication 10 minutes Evidence: moderate

Author Information

Author(s): Guldemond Nick A, Leffers Pieter, Walenkamp Geert HIM, Schaper Nicolaas C, Sanders Antal P, Nieman Fred HM

Primary Institution: University Hospital Maastricht, the Netherlands

Hypothesis

Can clinical and radiological measurements predict local peak pressure in diabetic patients?

Conclusion

Clinical and radiological measurements can explain only about 34 percent of the variance in local barefoot peak pressure in diabetic patients.

Supporting Evidence

  • Forefoot pressures were significantly higher in patients with neuropathy compared to those without.
  • Clinical models explained up to 39 percent of the variance in local peak pressures.
  • Callus formation and toe deformity were identified as relevant clinical predictors.

Takeaway

Doctors want to know how much pressure is on diabetic patients' feet to prevent ulcers, but they can't always tell just by looking or using standard tests.

Methodology

Ninety-three diabetic patients underwent clinical and radiological assessments, and their barefoot peak pressure was measured using a pressure platform.

Potential Biases

Potential bias due to the exclusion of patients with severe foot deformities.

Limitations

The prediction models were not useful in clinical practice due to significant underestimation of high plantar pressure values.

Participant Demographics

Patients aged 30-75 with diabetes mellitus type 1 or type 2.

Statistical Information

P-Value

p<0.005

Statistical Significance

p<0.005

Digital Object Identifier (DOI)

10.1186/1472-6823-8-16

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