Smoking, Alcohol, and Betel Quid and Oral Cancer: A Prospective Cohort Study
2011

Smoking, Alcohol, and Betel Quid's Link to Oral Cancer

Sample size: 10657 publication Evidence: high

Author Information

Author(s): Lin Wen-Jiun, Jiang Rong-San, Wu Shang-Heng, Chen Fun-Jou, Liu Shih-An

Primary Institution: Taichung Veterans General Hospital

Hypothesis

This study aimed to investigate the association between smoking, alcoholic consumption, and betel quid chewing with oral cancer.

Conclusion

Habitual smokers, alcohol consumers, and betel quid chewers have a significantly higher risk of developing oral cancer.

Supporting Evidence

  • The study enrolled 10,657 male participants.
  • 4.8% of participants had abnormal mucosa lesions.
  • 230 out of 344 participants who received biopsy were diagnosed with oral cancer.
  • Habitual smokers had an odds ratio of 46.87 for developing oral cancer.

Takeaway

If you smoke, drink alcohol, or chew betel quid, you have a much higher chance of getting oral cancer, so it's important to get regular check-ups.

Methodology

A prospective cohort study was conducted with male patients aged 18 and older, who underwent oral mucosa inspection and provided data on personal habits.

Potential Biases

Selection bias may exist due to the study's design and participant recruitment.

Limitations

The study was conducted at a single institution and only included male patients, limiting the external validity.

Participant Demographics

All participants were male, aged 18 to 96 years, with an average age of 55.2 years.

Statistical Information

P-Value

<0.001

Confidence Interval

31.84–69.00

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/525976

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