Sex Disparities in In‐Hospital Outcomes After Percutaneous Coronary Intervention (PCI) in Patients With Acute Myocardial Infarction and a History of Coronary Artery Bypass Grafting (CABG): A Cross‐Sectional Study
2024

Sex Differences in Hospital Outcomes After Heart Procedures

Sample size: 75185 publication 10 minutes Evidence: high

Author Information

Author(s): Yan Rui, Zhang Hui, Shi Bo, Ye Congyan, Fu Shizhe, Wang Kairu, Yang Jie, Yan Ru, Jia Shaobin, Ma Xueping, Cong Guangzhi

Primary Institution: Ningxia Medical University

Hypothesis

The in-hospital mortality rate among female patients would be higher than that among male patients.

Conclusion

Female patients who underwent PCI for AMI with a history of CABG had higher risks of in-hospital mortality, MACCEs, bleeding, and longer length of stay, especially among older patients.

Supporting Evidence

  • Female patients exhibited elevated risks of in-hospital mortality compared to male patients.
  • Female patients had a higher prevalence of major adverse cardiac or cerebrovascular events (MACCEs).
  • Female patients experienced longer hospital stays than male patients.

Takeaway

Women who have heart surgery tend to have more problems in the hospital than men, especially if they are older.

Methodology

The study used the National Inpatient Sample database to analyze hospitalizations for AMI with a history of CABG who underwent PCI from 2016 to 2019, employing 1:1 propensity score matching.

Potential Biases

Potential selection and observational biases due to the retrospective nature of the study.

Limitations

The study is based on administrative data, which may contain coding errors and lacks clinical details such as medication and imaging data.

Participant Demographics

The cohort included 74.77% male and 25.23% female patients, with female patients more likely to be Black and have lower socioeconomic status.

Statistical Information

P-Value

0.009

Confidence Interval

95% CI 1.14–1.93

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1002/hsr2.70292

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