Reply to Destaillats: Interesterified fats to replace trans fat
2007
Reply to Destaillats: Interesterified fats to replace trans fat
Commentary
Author Information
Author(s): Sundram Kalyana, Karupaiah Tilakavati, Hayes KC
Hypothesis
Does modifying triglyceride structure through interesterification affect glucose and insulin metabolism compared to natural saturated fats?
Conclusion
Modifying triglyceride structure by interesterification can significantly alter glucose and insulin metabolism in a short period.
Supporting Evidence
- The study emphasizes the importance of triglyceride structure in metabolic responses.
- Interesterified fats may have different metabolic outcomes compared to natural fats.
- Previous analyses did not adequately account for the effects of triglyceride structure on lipoprotein profiles.
Takeaway
Changing the way fats are made can change how our bodies handle sugar and insulin, even faster than natural fats.
Methodology
The study analyzed triglyceride species using HPLC coupled to an ELSD method and assessed plasma triglyceride samples for their sn-2 fatty acid content.
Limitations
The study's methodology may not have been as rigorous as other techniques like mass spectrometry.
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