Ingestion of micronutrient fortified breakfast cereal has no influence on immune function in healthy children: A randomized controlled trial
2011

Micronutrient Fortified Cereal and Immune Function in Children

Sample size: 73 publication Evidence: low

Author Information

Author(s): David C Nieman, Dru A Henson, Wei Sha

Primary Institution: Human Performance Lab, North Carolina Research Campus, Kannapolis, NC, USA

Hypothesis

School-aged children would experience improvements in immune function and a reduction in upper respiratory tract infections (URTI) during two months of supplementation with a fortified breakfast cereal.

Conclusion

Ingestion of breakfast cereal fortified with micronutrients does not significantly influence immune function or URTI rates in healthy children.

Supporting Evidence

  • Despite significant increases in nutrient intake, URTI rates did not differ between groups.
  • Pre- to post-study changes in immune function measures did not differ significantly.
  • The fortified cereal contributed significantly to total nutrient intake.

Takeaway

The study found that eating special cereal with added vitamins didn't help kids get sick less or improve their immune system.

Methodology

73 children aged 7-13 were randomized into three groups receiving different levels of fortified cereal for two months, with immune function measured before and after.

Potential Biases

No significant bias risks were reported.

Limitations

The sample size was considered marginal, and the study may not generalize to all populations.

Participant Demographics

73 children (42 males, 31 females) aged 7 to 13 years.

Statistical Information

P-Value

p=0.556

Statistical Significance

p=0.556

Digital Object Identifier (DOI)

10.1186/1475-2891-10-36

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