Intakes of fruits and vegetables, carotenoids and vitamins A, E, C in relation to the risk of bladder cancer in the ATBC cohort study
2002

Diet and Bladder Cancer Risk in Male Smokers

Sample size: 27111 publication Evidence: moderate

Author Information

Author(s): Michaud D S, Pietinen P, Taylor P R, Virtanen M, Virtamo J, Albanes D

Primary Institution: National Cancer Institute, Rockville, MD, USA

Hypothesis

Is there a relationship between dietary intakes of fruits, vegetables, carotenoids, and vitamins A, E, and C and the risk of bladder cancer among male smokers?

Conclusion

The study found no association between fruit and vegetable intake and the risk of bladder cancer among male smokers.

Supporting Evidence

  • 344 men developed bladder cancer during the study.
  • Consumption of fruits and vegetables was not associated with bladder cancer risk.
  • Intakes of vitamins A, C, E, and carotenoids were not related to bladder cancer risk.

Takeaway

Eating fruits and vegetables doesn't seem to help prevent bladder cancer in men who smoke.

Methodology

The study followed 27,111 male smokers over 11 years, using dietary questionnaires and Cox proportional hazards models to analyze the data.

Potential Biases

Potential confounding by smoking status and occupational exposures.

Limitations

Results may not be generalizable to non-smokers, and the study relied on self-reported dietary intake.

Participant Demographics

Male smokers aged 50-69 years.

Statistical Information

Confidence Interval

95% CI: 0.89–1.84

Digital Object Identifier (DOI)

10.1038/sj.bjc.6600604

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