DNA flow cytometry of breast cancer fine needle aspirates
1990
Concerns About DNA Flow Cytometry in Breast Cancer
Commentary
Author Information
Author(s): Y. Remvikos
Primary Institution: Institut Curie
Conclusion
The article by Mullen and Miller may confuse clinicians interested in DNA flow cytometry for breast cancer.
Supporting Evidence
- Previous studies on DNA flow cytometry in breast cancer were not referenced.
- Significant variations in DNA index should be defined with a threshold of at least 8%.
- Breast cancers are heterogeneous, which complicates the interpretation of DNA flow cytometry results.
Takeaway
This text discusses issues with a study on DNA testing in breast cancer, saying it could mislead doctors.
Potential Biases
The article may lead to confusion among clinicians due to its unclear definitions and lack of proper references.
Limitations
The article lacks references to previous work and does not adequately define variations in histograms.
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