Immune-Neuroendocrine Interactions and Autoimmune Diseases
Author Information
Author(s): Luis J. Jara, Carmen Navarro, Gabriela Medina, Olga Vera-Lastra, Francisco Blanco
Primary Institution: Hospital de Especialidades Centro Medico La Raza, IMSS, Mexico City, Mexico
Hypothesis
The interactions between the immune-neuroendocrine system have a major impact on the understanding of the pathogenic mechanisms, diagnosis, and therapy of autoimmune rheumatic diseases.
Conclusion
The study highlights the significant role of immune-neuroendocrine interactions in the pathogenesis and clinical expression of autoimmune rheumatic diseases.
Supporting Evidence
- Hormones, neuropeptides, and neurotransmitters participate in both innate and adaptive immune responses.
- High levels of pro-inflammatory hormones and cytokines are frequently detected in patients with autoimmune rheumatic diseases.
- Hormonal changes may appear before the symptomatic phase of autoimmune diseases.
Takeaway
This study explains how hormones and the immune system work together and how their interactions can lead to autoimmune diseases.
Methodology
The review analyzes existing literature on the immune-neuroendocrine system and its role in autoimmune diseases.
Limitations
The review is based on existing literature and may not include all recent studies or findings.
Digital Object Identifier (DOI)
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