PKreport: report generation for checking population pharmacokinetic model assumptions
2011

PKreport: A Tool for Population Pharmacokinetic Model Analysis

publication Evidence: moderate

Author Information

Author(s): Sun Xiaoyong, Li Jun

Primary Institution: Iowa State University, Université de Montréal

Hypothesis

The study aims to develop an R package that automates the generation of reports for population pharmacokinetic models.

Conclusion

PKreport is an R package that efficiently generates plots and statistics for testing model assumptions and diagnosing population pharmacokinetic models.

Supporting Evidence

  • PKreport provides a flexible R class to store and retrieve NONMEM 7 output.
  • The package automates the generation of plots for visualizing data and models.
  • It includes an archive-oriented management tool for users to store and modify figures.
  • High-quality graphs are generated using R packages like lattice and ggplot2.

Takeaway

PKreport is like a smart helper that makes it easier for scientists to check if their medicine models are working right by creating helpful pictures and reports.

Methodology

The package automates exploratory data analysis, goodness of fit plots, and various model diagnostics using R.

Digital Object Identifier (DOI)

10.1186/1472-6947-11-31

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