Antimicrobial Resistance Patterns of Staphylococcus aureus in KwaZulu-Natal, South Africa
Author Information
Author(s): Shittu Adebayo O, Lin Johnson
Primary Institution: University of KwaZulu-Natal
Hypothesis
What are the antibiotic susceptibility patterns of Staphylococcus aureus isolates in KwaZulu-Natal province?
Conclusion
The study found high resistance rates of MRSA to several antibiotics, indicating that treatment options for MRSA infections in this province are limited.
Supporting Evidence
- All isolates were susceptible to vancomycin, teicoplanin, and fusidic acid.
- 26.9% of isolates were confirmed as MRSA.
- More than 80% of MRSA were resistant to at least four classes of antibiotics.
- The inducible MLSB phenotype was detected in 10.8% of MSSA and 82% of MRSA.
- Continuous surveillance on resistance patterns is crucial for understanding new trends.
Takeaway
This study looked at how well Staphylococcus aureus bacteria respond to antibiotics in KwaZulu-Natal, South Africa, and found that many of them are resistant to common treatments.
Methodology
The study used the disk-diffusion technique to test the in-vitro activities of 20 antibiotics against 227 S. aureus isolates from clinical samples.
Limitations
A comparative analysis of MRSA based on the geographic location of the health institutions could not be determined due to varying numbers obtained.
Participant Demographics
The study included isolates from 14 provincial hospitals located in seven districts in KwaZulu-Natal province.
Digital Object Identifier (DOI)
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