Prematurity and Intraamniotic Infection: Is There a Correlation?
Author Information
Author(s): Susan M. Cox, Scott Roberts, Percilis Roussis, Berry A. Campbell, Thomas E. Curry, Jr.
Primary Institution: University of Kentucky
Hypothesis
Does subclinical intraamniotic infection affect fetal behavioral patterns?
Conclusion
The study found no correlation between fetal biophysical parameters and subclinical intraamniotic infection.
Supporting Evidence
- 20% of patients with PPROM had laboratory signs of infection.
- 10% of patients with PPROM had a positive amniotic fluid culture.
- Inflammatory cytokines were elevated in patients with subclinical chorioamnionitis.
Takeaway
The study looked at whether infections in pregnant women affect how babies move and breathe before birth, but it found no clear link.
Methodology
Amniotic fluid was collected from patients with preterm labor and analyzed for infection and cytokine levels.
Limitations
The small sample size may limit the ability to detect significant differences.
Participant Demographics
Patients with preterm labor and premature rupture of membranes, including both infected and non-infected groups.
Statistical Information
P-Value
0.005
Statistical Significance
p<0.05
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