Local Recurrences After Treatment of Giant Cell Tumors in Long Bones
Author Information
Author(s): Kabul C Saikia, Tulsi D Bhattacharyya, Sanjeev K Bhuyan, Bikas Durgia, Bharat Ahmed Firoz
Primary Institution: Gauhati Medical College
Hypothesis
This study aimed to analyze the rates of local recurrence and its possible predisposing factors in Campanacci’s Grade III and II GCT of long bones following intralesional curettage and bone cementing.
Conclusion
We observed a higher rate of local recurrence with Campanacci’s Grade III GCTs, suggesting selective use of this procedure in Grade III lesions.
Supporting Evidence
- Eleven patients (34.4%) had local recurrence, with a mean recurrence time of 14 months.
- The two-year recurrence-free survivorship was 71.9% (n=23/32).
- Grade III lesions accounted for eight of the eleven recurrences.
Takeaway
This study looked at patients with a type of bone tumor and found that those with more aggressive tumors had a higher chance of the tumor coming back after treatment.
Methodology
The study involved 32 patients with Grade II and III GCTs treated with intralesional curettage and bone cementing, followed for an average of 6.5 years.
Limitations
The study had a small sample size and included patients with varying degrees of tumor aggressiveness.
Participant Demographics
18 men and 14 women, mean age 32.4 years.
Statistical Information
P-Value
0.966
Digital Object Identifier (DOI)
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