Monitoring Hearing in Adults with AIDS on Antiretroviral Therapy
Author Information
Author(s): Khoza-Shangase Katijah
Primary Institution: University of the Witwatersrand
Hypothesis
The participants’ hearing function before and after antiretroviral drug-use would remain the same.
Conclusion
The study found significant changes in hearing function in adults with AIDS receiving antiretroviral therapy, indicating the need for closer monitoring.
Supporting Evidence
- Statistically significant changes were found in the experimental group for pure tone audiometry at high frequencies.
- Clinically significant changes were observed in distortion product otoacoustic emissions in the experimental group.
- The control group showed no statistically or clinically significant changes in hearing.
Takeaway
This study looked at how HIV medicine might affect hearing in people. It found that some people might have hearing changes even if they seem fine.
Methodology
Participants underwent audiological assessments including pure tone audiometry and distortion product otoacoustic emissions at baseline, three months, and six months after starting treatment.
Potential Biases
There was no random selection of participants, which could introduce bias.
Limitations
The study had a small control group and did not include ultra-high frequency audiometry, which may have affected the results.
Participant Demographics
Adults aged 18 to 50 years, with HIV/AIDS, receiving or not receiving antiretroviral therapy.
Statistical Information
P-Value
0.04
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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