Macular pigment response to a supplement containing meso-zeaxanthin, lutein and zeaxanthin
2007

Effects of a Supplement with Meso-Zeaxanthin on Macular Pigment Density

Sample size: 19 publication Evidence: moderate

Author Information

Author(s): Richard A Bone, John T Landrum, Yisi Cao, Alan N Howard, Francesca Alvarez-Calderon

Primary Institution: Florida International University

Hypothesis

Can a supplement containing meso-zeaxanthin, lutein, and zeaxanthin effectively raise macular pigment density in human subjects?

Conclusion

The study demonstrates that a supplement with meso-zeaxanthin is effective at increasing macular pigment density, which may help protect against age-related macular degeneration.

Supporting Evidence

  • Subjects taking the supplement showed a significant increase in macular pigment density.
  • Blood tests confirmed the absorption of meso-zeaxanthin into the serum.
  • The placebo group did not show significant changes in macular pigment density.

Takeaway

This study shows that taking a special vitamin can help make your eyes healthier by increasing a protective pigment in your eyes.

Methodology

A 120-day study with 10 subjects taking a supplement and 9 subjects taking a placebo, measuring blood serum and macular pigment density.

Potential Biases

Potential bias due to non-random assignment of subjects to treatment and placebo groups.

Limitations

The study did not use a standard double-blind design and had a small sample size.

Participant Demographics

8 male and 2 female subjects aged 21 to 58 years, with a mean age of 30.5 years.

Statistical Information

P-Value

p<0.002

Statistical Significance

p<0.002

Digital Object Identifier (DOI)

10.1186/1743-7075-4-12

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