Effect of fruit and vegetable concentrates on endothelial function in metabolic syndrome: A randomized controlled trial
2011

Effects of Fruit and Vegetable Concentrates on Heart Health

Sample size: 64 publication Evidence: low

Author Information

Author(s): Ali Ather, Yazaki Yuka, Njike Valentine Y, Ma Yingying, Katz David L

Primary Institution: Prevention Research Center, Yale University School of Medicine, Griffin Hospital

Hypothesis

Encapsulated fruit and vegetable concentrates can provide cardioprotective benefits similar to the effects of regular consumption of whole fruits and vegetables.

Conclusion

Encapsulated fruit and vegetable juice powder concentrates did not alter insulin or glucose measures in this sample of adults with metabolic syndrome.

Supporting Evidence

  • No significant between-group differences in endothelial function with daily treatment for 8 weeks were seen.
  • No other significant treatment effects were discerned in glucose, insulin, lipids, and weight.
  • Subjects were pre-diabetic with a mean fasting plasma glucose of 115 mg/dL.

Takeaway

Eating special fruit and vegetable powders didn't help people's heart health as expected.

Methodology

Randomized, double blind, placebo controlled crossover clinical trial with three treatment arms.

Potential Biases

The sample was largely Caucasian and from a suburban community, which may limit generalizability.

Limitations

The study had a relatively homogenous sample and lacked data on dietary and exercise habits.

Participant Demographics

64 adults with metabolic syndrome, 52% female, mean age 56.9 years.

Statistical Information

Statistical Significance

p > 0.05

Digital Object Identifier (DOI)

10.1186/1475-2891-10-72

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