PRRS Virus Variants in Vietnam and China
Author Information
Author(s): Feng Youjun, Zhao Tiezhu, Nguyen Tung, Inui Ken, Ma Ying, Nguyen Thi Hoa, Nguyen Van Cam, Liu Di, Bui Quang Anh, To Long Thanh, Wang Chuanbin, Tian Kegong, Gao George F.
Primary Institution: Institute of Microbiology–Chinese Academy of Sciences, Beijing, People’s Republic of China
Hypothesis
What are the characteristics of PRRS virus outbreaks in Vietnam and China in 2007?
Conclusion
Nearly identical variants of NA-type PRRSVs caused the PRRS epidemics in Vietnam and China in 2007.
Supporting Evidence
- PRRS has caused significant economic losses in the swine industry.
- The 2006 PRRS outbreaks in China involved over 2 million pigs.
- All samples collected were positive for PRRSV.
- The 2007 Vietnamese isolate showed 99% identity to 2006 PRRS isolates in China.
- Clinical signs in affected pigs included high fever and depression.
- Genomic analysis revealed a unique discontinuous deletion of 30 amino acids in Nsp2.
Takeaway
There was a pig disease outbreak in Vietnam and China that affected many pigs, and the viruses causing it were very similar.
Methodology
Genomic analysis and PCR-based detection were used to identify and characterize the PRRSV isolates.
Limitations
The origin of the lethal variants in Vietnam is still unclear.
Participant Demographics
The study involved pigs affected by PRRS in Vietnam and China.
Digital Object Identifier (DOI)
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